Marvelous Stem Cells and Infertility

22 January 2020 Written by
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Stem cells and infertility is a new wondrous subject. Women who are fertile experience a natural period of fertility before and during ovulation, and they are naturally infertile during the rest of the menstrual cycle. Infertility primarily refers to the biological inability of a person to contribute to conception.

Stem cells and infertility in recent years has resulted in stem-cell therapy raising new hope in the field of reproductive disability management, which is infertility that may also refer to the state of a woman who is unable to carry a pregnancy to full term. Infertility is the inability to conceive after more than a year of unprotected sex using no birth control.

According to the Centers for Disease Control and Prevention (CDC), almost 9 percent of men suffer from infertility. Nearly 72.4 million people or 15% of couples experience fertility problems . Treatment. In recent years, several advancements have been made in assisted reproduction treatment and now more than 80% of couples experiencing infertility issues can conceive a child.

Causes of Infertility

There are many biological causes of infertility, including some that medical intervention can treat. The causes of infertility vary widely, but the most common culprits are hormonal disorders, genetic disorders and a disruption of testicular or ejaculatory function.

As infertility is a heterogeneous condition, caused by various underlying pathologies, it is possible that some of the mechanisms leading to infertility also play a role in the etiology of this outcome.


Azoospermia is defined as the complete lack of sperm in the ejaculate. In humans, Azoospermia affects about 1% of the male population and may be seen in up to 20% of male infertility situations. In testicular Azoospermia the testes are abnormal, atrophic, or absent, and sperm production severely disturbed to absent.

Male infertility accounts for approximately half of all cases of infertility, and nonobstructive azoospermia is the most severe form. Besides genetic factors, azoospermia also occurs due to injuries, exposure to toxicants, immunosuppression and anticancer treatment.

Stem Cell Research

Stem cell research is growing exponentially because of the potential that stem cells hold. Stem cells are unspecialized cells so they can renew on their own through cell division. And they can repair many tissues due to their regenerative property, which allows them to replenish other cells without limit. Also, they can be manipulated to become specialized cells like brain cells or red blood cells or tissues.

Research into these potent abilities of stem cells has led to new medical knowledge that can be used to treat diseases like heart disease, diabetes and infertility. Studies on using stem cells to treat infertility in men are based on stimulating the cells to produce sperm that can be used in reproduction treatments for infertility.

Stem Cells as New Agents for the Treatment of Infertility

Due to their unlimited source and high differentiation potential, stem cells are considered as potentially new therapeutic agents for the treatment of infertility. Stem cells could be stimulated in vitro to develop various numbers of specialized cells including male and female gametes suggesting their potential use in reproductive medicine.

Stem cells to the rescue of female infertility

Stem cell-based strategies for ovarian regeneration and oocyte production have been proposed as future clinical therapies for treating infertility in women. The pioneering work by Scientists has identified a rare population of mitotically active germ cells in human ovaries that can be purified and cultured in vitro to spontaneously form oocytes.

Ability to generate new oocytes, the treatment of Asherman syndrome and recurrent implantation failures due to poor endometrial receptivity have all been addressed with the treatment of stem cells in various research centers across the globe.


The potential of stem cell therapies has made leaps and bounds in terms of progress. One of the most exciting potential approaches of stem cells therapy is that cells that exist throughout the body can create our components, including tissues and blood cells. That could help men who cannot produce sperm and women with infertility issues.

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